Health

FDA Approves Moderna’s mFlusiva: The First mRNA Flu Vaccine

The FDA approved Moderna’s mFlusiva in August 2026, the first mRNA-based seasonal flu vaccine, for adults 50 and older, based on a Phase 3 trial of more than 4…

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PANDEMIC

The 1918 Pandemic Establishes the Stakes

An H1N1 virus killed an estimated 50 million people worldwide -- the historical baseline behind every flu vaccine effort since.

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FIRST VACCINE

The First Licensed Flu Vaccine

Egg-based manufacturing, developed with US Army-funded research, becomes the founding platform for flu vaccination.

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KEY DISCOVERY

Kariko and Weissman’s mRNA Breakthrough

Modified-nucleoside chemistry solves mRNA’s inflammation problem -- later recognized with the 2023 Nobel Prize.

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MODERNA FOUNDED

Moderna Therapeutics Is Founded

Built on mRNA research, years before any mRNA vaccine had ever been licensed anywhere in the world.

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NEW PLATFORMS

Cell-Based and Recombinant Vaccines Arrive

Flucelvax and Flublok diversify flu vaccine manufacturing beyond eggs for the first time in 70 years.

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PLATFORM PROVEN

COVID-19 mRNA Vaccines Reach Millions

The FDA authorizes Moderna’s COVID-19 vaccine, generating years of real-world mRNA safety data.

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PIVOTAL TRIAL

The 40,000-Person Phase 3 Trial Begins

Moderna launches its pivotal trial for mRNA-1010 in adults 50 and older across multiple countries.

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FDA APPROVAL

FDA Approves mFlusiva

The first mRNA seasonal flu vaccine is licensed for adults 50 and older -- traditional and accelerated approval.

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